Japan - Osaka, Japan · last month
Lead hands-on engineering of production GenAI and agentic AI systems for AstraZeneca Japan's commercial, medical and field teams, owning reliability, cost and security while coaching engineers. Work includes building evaluations, agent architecture and AWS-based operations.
Job Description The Agentic AI Lead is the senior hands-on engineer in the Enterprise AI Technology Delivery team. The role designs, builds, evaluates and operates GenAI and agentic AI systems that AstraZeneca Japan's commercial, medical and field organizations rely on in production, and raises the engineering practice of the team that builds them. This is a building role: the majority of the Lead's time is spent in code, traces and evaluation data, not in coordination. The Lead takes ownership of the team's existing AI platform assets and key systems for business users. The Lead is also accountable for their reliability, cost and security. The Lead works autonomously with limited supervision, provides technical direction and coaching to the team's AI engineers, and partners with business owners to make sure what gets built solves a validated business problem. Experience Mandatory 1. 5+ years building and running software in production (Python; AWS or equivalent cloud). 2. 2+ years hands-on shipping LLM-based or agentic applications to real users, not only proofs of concept. 3. Evaluation-driven practice: can show an evaluation set, error analysis and the iteration it drove on a real project. 4. Daily use of agentic coding tools (Claude Code, Codex or equivalent) as a core part of engineering work, including reviewing and testing their output. 5. Experience leading a technical workstream or mentoring engineers (formal team-lead experience not required; this is a hands-on role, ~80% coding / 20% coordination, suited to a strong developer ready to grow into a lead). Nice to have Trained, evaluated or maintained supervised or deep-learning models in production. Experience in pharma or another regulated industry . Experience co-developing with external delivery partners or vendors. Front-end development (React/Next.js) for agent user interfaces. License Mandatory None. Bachelor's degree in Computer Science or a related quantitative discipline, or equivalent experience. Nice to have AWS certification (Solutions Architect Associate or Developer Associate, or higher). Master's or PhD in Computer Science or a related quantitative discipline. DeepLearning.AI or equivalent LLM/agentic AI coursework. Skill-set Mandatory Agent architecture: workflow vs. agent harness, tool calling, MCP, memory and context management, guardrails against prompt injection and data exfiltration. At least one agent framework ( Bedrock AgentCore, LangGraph, OpenAI Agents SDK, or equivalent). Grounding: RAG with vector stores and retrieval over structured data via SQL. LLM foundations: model selection, tokenisation and cost, context window and caching, when to fine-tune or self-host. Production operations for AI systems: observability and tracing, cost/latency optimisation, statistical regression testing in CI/CD, prompt/model versioning, infrastructure-as-code. Software engineering fundamentals: full-stack application design, data modelling, testing strategy, secure-by-design practice (dependency scanning, secrets hygiene). AWS in production: Lambda, ECS/Fargate, API Gateway, Bedrock, IAM. Clear written and verbal explanation of technical trade-offs and uncertainty to non-specialists. Nice to have Knowledge graphs or semantic layers over structured data (e.g. Snowflake). Document-processing pipelines for Japanese-language material. Customising agent environments: skills, MCP servers, hooks, shared context files (CLAUDE.md/AGENTS.md). Eval/tracing tooling such as Langfuse, Braintrust or LangSmith. Azure OpenAI and multi-provider gateway experience. Languages Mandatory Japanese：Business level. For non-native speakers: JLPT N2 or higher (N1 preferred). Native-level Japanese for business stakeholdesr English：Business level (technical documentation, working with global AZ teams). Date Posted 17-9月-2026 Closing Date AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.
Posted Sep 16, 2026
